
The Substance
2024 · Movie · R · 141 min · ★ 7.1
A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.
Also known as La Substance
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Streaming on HBO Max and MUBI — or rent from $5.99.
2 hours to watch.
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Details
- Years
- 2024
- Release date
- 2024-09-07
- Language
- English
- Rated
- R
- Runtime
- 141 min
- Max quality
- UHD
- TMDB rating
- 7.1/10 (6,059 votes)
- Budget
- $17,500,000
Themes
- new year's eve
- capitalism
- birthday
- black market
- identity
- dark comedy
- beauty
- satire
- aging
- celebrity
- female protagonist
- los angeles, california
- +15 more
Awards & recognition
- Golden Globe Award — Best Actor – Motion Picture Musical or Comedy · 2025
- Best Screenplay Award · 2024
- Academy Award — Best Picture · 2025 · nominated
- Academy Award — Best Makeup and Hairstyling · 2025 · nominated
- European Film Award — Best Film · 2024 · nominated
Cast & crew

Demi Moore
as Elisabeth

Margaret Qualley
as Sue

Dennis Quaid
as Harvey

Edward Hamilton-Clark
as Fred

Gore Abrams
as Oliver

Oscar Lesage
as Troy

Christian Erickson
as Man at Diner

Robin Greer
as Male Nurse

Tom Morton
as Doctor

Hugo Diego Garcia
as Diego - Boyfriend
Directed by Coralie Fargeat