
Splice
2009 · Movie · R · 104 min · ★ 5.9 · 71% critics
Two rebellious scientists push past legal and ethical limits by splicing human and animal DNA to create a new organism. Their rapidly developing creation, named Dren, grows from a deformed infant into a beautiful but dangerous winged human-chimera, forming a bond with its creators that turns deadly.
Also known as Nouvelle espèce
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Details
- Years
- 2009
- Release date
- 2010-06-03
- Language
- English
- Rated
- R
- Runtime
- 104 min
- Critic score
- 71/100
- TMDB rating
- 5.9/10 (2,440 votes)
- Box office
- $27,127,620
- Budget
- $30,000,000
About
You’ll likely enjoy Splice if you want a tense, unsettling take on genetic experimentation and its consequences, but Not for you if you want a neatly satisfying arc or if you dislike dark, morally fraught sci-fi like Annihilation or Crimes of the Future.
Pros: tense ethical sci-fi premise; disturbing creature design; strong lead performances | Cons: uneven and sometimes silly script; predictable story beats; divisive emotional payoff
Themes
- experiment
- genetics
- dna
- gene manipulation
- genetic engineering
- disturbed
- grim
- genetically modified organism
- absurd
- disgusted
- distressing
Awards & recognition
- Sitges Film Festival best special effects award · 2009
Cast & crew

Adrien Brody
as Clive

Sarah Polley
as Elsa

Delphine Chanéac
as Dren

David Hewlett
as Barlow

Abigail Chu
as Young Dren

Stephanie Baird
as Elsa / PD

Brandon McGibbon
as Gavin

Amanda Brugel
as Melinda Finch

Simona Măicănescu
as Joan Chorot
Directed by Vincenzo Natali