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Splice

2009 · Movie · R · 104 min · ★ 5.9 · 71% critics

HorrorScience Fiction

Two rebellious scientists push past legal and ethical limits by splicing human and animal DNA to create a new organism. Their rapidly developing creation, named Dren, grows from a deformed infant into a beautiful but dangerous winged human-chimera, forming a bond with its creators that turns deadly.

Also known as Nouvelle espèce

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Details
Years
2009
Release date
2010-06-03
Language
English
Rated
R
Runtime
104 min
Critic score
71/100
TMDB rating
5.9/10 (2,440 votes)
Box office
$27,127,620
Budget
$30,000,000
About

You’ll likely enjoy Splice if you want a tense, unsettling take on genetic experimentation and its consequences, but Not for you if you want a neatly satisfying arc or if you dislike dark, morally fraught sci-fi like Annihilation or Crimes of the Future.

Pros: tense ethical sci-fi premise; disturbing creature design; strong lead performances | Cons: uneven and sometimes silly script; predictable story beats; divisive emotional payoff

Themes

  • experiment
  • genetics
  • dna
  • gene manipulation
  • genetic engineering
  • disturbed
  • grim
  • genetically modified organism
  • absurd
  • disgusted
  • distressing

Awards & recognition

  • Sitges Film Festival best special effects award · 2009

Cast & crew

Directed by Vincenzo Natali