
Splice
2009 · Movie · R · 104 min
★ 5.9(2,546)unSUB Rating
Two rebellious scientists push past legal and ethical limits by splicing human and animal DNA to create a new organism. Their rapidly developing creation, named Dren, grows from a deformed infant into a beautiful but dangerous winged human-chimera, forming a bond with its creators that turns deadly.
Also known as Nouvelle espèce
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Details
- Years
- 2009
- Release date
- 2010-06-03
- Language
- English
- Rated
- R
- Runtime
- 104 min
- TMDB rating (input)
- 5.9/10 (2,546 votes)
- Box office
- $27,127,620
- Budget
- $30,000,000
About
You’ll likely enjoy Splice if you want a tense, unsettling take on genetic experimentation and its consequences, but Not for you if you want a neatly satisfying arc or if you dislike dark, morally fraught sci-fi like Annihilation or Crimes of the Future.
Pros: tense ethical sci-fi premise; disturbing creature design; strong lead performances | Cons: uneven and sometimes silly script; predictable story beats; divisive emotional payoff
Themes
- rape
- experiment
- genetics
- dna
- laboratory
- scientist
- dead cat
- gene manipulation
- genetic engineering
- death of pet
- sexual assault
- disturbed
- +7 more
Awards & recognition
- Sitges Film Festival best special effects award · 2009
Cast & crew

Adrien Brody
as Clive Nicoli

Sarah Polley
as Elsa Kast

Delphine Chanéac
as Dren

Brandon McGibbon
as Gavin Nicoli

Simona Măicănescu
as Joan Chorot

David Hewlett
as William Barlow

Abigail Chu
as Child Dren

Stephanie Baird
as Elsa / PD
- DH
Doug Hicton
as Lab tech (uncredited)

Amanda Brugel
as Melinda Finch
Directed by Vincenzo Natali